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本文采用双抗体央心 ELISA 法检测了26例慢活肝和肝炎后肝硬化患者血清肿瘤坏克因子。结果显示:慢活肝和肝炎后肝硬化患者血清肿瘤坏死因子水平均高于正常对照(P<0.05);而慢活肝与肝硬化两组之间肿瘤坏死因子水平无显著差异(P>0.05)。当肝细胞损伤明显、ALT 高于正常时,则肿瘤坏死因子水平显著高于正常人(P<0.01)。提示肿瘤坏死因子检测可反映慢性肝病活动程度。
In this paper, double antibody central ELISA was used to detect serum tumor necrosis factor in 26 patients with chronic liver and posthepatitic cirrhosis. The results showed that the levels of serum tumor necrosis factor in patients with chronic liver failure and cirrhosis after hepatitis were higher than those in normal controls (P <0.05), while there was no significant difference between the two groups (P> 0.05 ). When liver cell injury was obvious, ALT was higher than normal, the level of tumor necrosis factor was significantly higher than normal (P <0.01). Tumor necrosis factor test may reflect the degree of chronic liver disease activity.