慢性铍病是以铍作业者发病的肺间质性类上皮细胞性肉芽肿病变为主要特征的疾病。本病最初是由Hardy、Tabershow氏(1946)报道,其后50年代中期报道了较多的病例。关于本病的发生机理,有关由敏所致的细胞性免疫早就引人注目,近年尤其是从体液性免疫方面也报道了有意义的见解。作者等为了阐明关于慢性铍病患者的淋巴细胞转化试验(LST)、 Chronic beryllium disease is a disease characterized mainly by the pathogenesis of interstitial interstitial cystic granuloma of the beryllium operator. The disease was originally reported by Hardy, Tabershow (1946), followed by more cases reported in the mid-1950s. About the pathogenesis of this disease, cellular immunity caused by allergy has drawn attention for a long time. In recent years, meaningful insights have also been reported in terms of humoral immunity. In order to clarify the lymphocyte transformation test (LST) in patients with chronic beryllium disease,