By avoiding or reducing the production of waste, waste minimization is an effective approach to solve the pollution problem in chemical industry. Process integration supported by multi-objective optimization provides a framework for process design or process retrofit by simultaneously optimizing on the aspects of environment and economics. Multi-objective genetic algorithm is applied in this area as the solution approach for the multi-objective optimization problem. By avoiding or reducing the production of waste, waste minimization is an effective approach to solve the pollution problem in chemical industry. Process integration supported by multi-objective optimization provides a framework for process design or process retrofit by when optimizing on the aspects of environment and economics. Multi-objective genetic algorithm is applied in this area as the solution approach for the multi-objective optimization problem.