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本文主要介绍了Ｉ型胶原吡啶并啉交联的研究进展，阐述了它的生化基础，测定方法及不同生理、病理条件下的变化。
This article mainly introduces the research progress of the crosslinking of type I collagen pyridinoline, and expounds its biochemical basis, determination methods and changes under different physiological and pathological conditions.