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目的 了解前列腺增生(BPH)中前列腺上皮内瘤(PIN)的CT灌注成像表现,并初步探讨PIN与前列腺癌(PCa)及良性BPH的灌注成像表现的关系.资料与方法 BPH25例,其中PIN样变9例,良性BPH 16例.PCa 34例,行前列腺病变中心层面灌注扫描,得到各组灌注图(PF)、强化峰值图(PEI)、达峰时间图(TTP)、血容量(BV)值和时间密度曲线(TDC),并对各组灌注值进行对比分析.结果 PIN的PF值大于良性BPH,TTP值小于良性BPH,差异有统计学意义.PIN的TTP值大于PCa组,PF值小于PCa组,差异有统计学意义. 结论 PIN的CT灌注成像表现提示,PIN的PF值和邢值与PCa和良性BPH不同,介于两者间.这种灌注特征可能为早期发现PCa提供一定帮助.“,”Objective To understand the CT perfusion imaging performance of prostatic intraepithelial neoplasia (PIN) in benign prostatic hyperplasia (BPH) and to explore the relationship between PIN,PC and BPH in the perfusion imaging performance. Materials and Methods All cases underwent routine CT pain scan and perfusion CT scan. The patients were divided into BPH group (25 eases,9 cases of PIN were included) ,and PC group (34cases). All the original maps of perfusion CT scan were transferred to an outline workstation to create color perfusion maps and to measure the blood flow parameters containing PF,PEI,TTP, BV of the prostate cortex and medulla using the function CT software. Results The PF value of PIN was greater than that of benign BPH. The TTP value of PIN was less than that of benign BPH. The differences between PIN and BPH in the TIP value and the PF value had statistical significance. The TrP value of PIN is greater than that of PC group and the PF value is less than that of PC group, which had statistical significant differences. Conclusion The performance of CT perfusion imaging in PIN is different from that of benign BPH and PC. The features of the CT perfusion imaging may be useful for the early detection of PC.