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目的研究中药杜仲在治疗创伤性骨折方面有无促进骨折愈合的作用。方法手术造出日本大耳白兔胫骨中下1/3段交界处骨折及骨缺损模型45只,随机分成治疗组和对照组,分别给予杜仲水煎液及生理盐水灌胃,并在造模后7d、17d、27d、37d、47d分别进行X线摄片,对其半计量数据进行统计学分析。结果治疗组(n=23)与对照组(n=22)相比较,在第7天时骨折断端的X线影像学无明显差异(P>0.05),第17天以后实验组骨痂影像明显多于对照组(P<0.05或P<0.01)。结论杜仲水煎液内服能促进兔创伤性骨折的愈合。
Objective To study the effect of Chinese medicine Eucommia on the healing of fractures in the treatment of traumatic fractures. METHODS: Forty-five models of fractures and bone defects at the mid-lower 1/3 segment of the humerus of Japanese big ear rabbits were randomly divided into treatment group and control group. The rats were given intragastric administration of eucommia ulmoides decoction and normal saline respectively. After 7d, 17d, 27d, 37d, and 47d, X-ray radiographs were taken. The semi-quantitative data were analyzed statistically. Results Compared with the control group (n=22) in the treatment group (n=23), there was no significant difference in X-ray image of the fractured end on the 7th day (P>0.05). After the 17th day, the imaging of the epiphysis was obvious in the experimental group. More than the control group (P <0.05 or P <0.01). Conclusion Oral decoction of Eucommia ulmoides can promote the healing of traumatic fracture in rabbits.