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1998年3月5~7日第四届国际肾综合征出血热(HFRS)及汉坦病毒(Hantaviruses,HV)会议在美国亚特兰大召开,交流了1995年6月第三届会议后3年来在有关HV感染(HFRS及HPS)与HV研究方面的新进展,来自世界各国的250余名代表参加了会议,我国有7位专家应邀参加会议。此次会议由美国疾病控制和预防中心(CDC)负责组织,会议按内容分9个部分进行交流:临床、发现机理和免疫应答,实验诊断,生态学,流行病学,健康教育和预防,病毒/宿主遗传性分析,分子生物学和细胞相互作用,抗病毒药物和疫苗研制。我国学者通过大会报告或墙展介绍了我国在疫苗,流行病学(包括螨媒)、分子生物学等方面的研究进展和经验。本文从流行病学、汉坦病毒的遗传和分子生物学及汉坦病毒的致病性和免疫应答、抗病毒药物和疫苗三个方面介绍国外主要的研究新进展。
March 4-7, 1998 The 4th International Meeting of Hemorrhagic Fever with Hemorrhagic Fever with Renal Hemorrhagic Fever (HFRS) and Hantavirus (Hantaviruses, HV) was held in Atlanta, United States during the three years since its third meeting in June 1995 More recent advances in HV infection (HFRS and HPS) and HV research were attended by more than 250 delegates from all over the world. Seven experts from China were invited to attend the conference. Organized by the Centers for Disease Control and Prevention (CDC), the conference is organized in 9 parts: clinical, discovery mechanisms and immune responses, laboratory diagnostics, ecology, epidemiology, health education and prevention, viruses / Hereditary analysis of hosts, molecular biology and cell-cell interactions, antiviral drugs and vaccine development. Our scholars introduced the research progress and experience in vaccines, epidemiology (including mite media) and molecular biology in China through the report of the conference or wall show. This article introduces the major advances in foreign research from three aspects: epidemiology, genetic and molecular biology of Hantavirus, pathogenicity and immune response of Hantavirus, antiviral drugs and vaccines.