背景　感染是终末期肾病的常见并发症 ,以革兰氏阳性球菌及革兰氏阴性杆菌感染最常见 ,常用的治疗方案是静脉使用万古霉素加氨基糖甙类抗生素 ,治疗的副作用主要是耳毒性及肾毒性。头孢曲松为第 3代头孢类广谱抗炎药 ,本文着重了解其在预防与处理终末期肾病感染中的应用效果。 Background infection is a common complication of end-stage renal disease, Gram-positive cocci and Gram-negative bacilli infection is the most common and commonly used treatment is intravenous vancomycin plus aminoglycoside antibiotics, the main side effects of treatment are ear Toxicity and nephrotoxicity. Ceftriaxone is the third generation of cephalosporins broad-spectrum anti-inflammatory drugs, this article focuses on its prevention and treatment of end-stage renal disease in the application of the effect.