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有关健康人外周血淋巴细胞上颗粒酶存在的问题有一些争论的报道，此文的研究是应用针对人类天然ＧｒＢ的单克隆抗体分析了健康人Ｔ细胞中ＧｒＢ的表达，并分析了ＣＤ８＋ＧｒＢ＋Ｔ细胞亚群的表型及对自发凋亡和Ｆａｓ介导的凋亡的易感性。方法：从人类ＮＫＣ系ＹＴＩＮＤＹ
Some controversy has been reported about the presence of granzymes on peripheral blood lymphocytes in healthy humans. In this paper, GrB expression in healthy human T cells was analyzed using a monoclonal antibody directed against human natural GrB. The effects of CD8 + GrB + T cell subsets Population phenotype and susceptibility to spontaneous apoptosis and Fas-mediated apoptosis. Methods: Human NKC line YT INDY