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许多学者认为脑PET显像不仅能诊断癫痫,且能对癫痫灶准确定位,为癫痫的手术、立体定向和放射外科治疗提供了定位依据。本研究分析了12例难治性癫痫患者术前~(18)F-FDG PET脑显像与术中皮层脑电图(ECoG)检查、术后病理结果的关系,以探讨术前~(18)F-FDG PET脑显像对癫痫灶定位的价值。1 资料与方法1.1 临床资料 本组共12例,男8例,女4例,年龄4～48岁,平均21.5岁;病程1.5～20年,平均4.5年;发作类型按照国际癫痫分类标准:全身性发作6例,复杂部分性发作4例,单纯部分性发作1例,部分性发作继发全身性发作1例;均长期服用抗癫痫药物治疗,临床诊断为难治性癫痫,有明确的手术适应症;术前所有患者均行2～5次EEG或动态
Many scholars believe that brain PET imaging can not only diagnose epilepsy, and can accurately locate the epileptic foci, providing the basis for the surgical, stereotactic and radiosurgery treatment of epilepsy. This study analyzed the relationship between preoperative 18 F-FDG PET imaging and intraoperative cortical EEG (ECoG) and postoperative pathological findings in 12 patients with intractable epilepsy. ) F-FDG PET brain imaging on the localization of epileptic foci. 1 Materials and Methods 1.1 Clinical data The group of 12 cases, 8 males and 4 females, aged 4 to 48 years, mean 21.5 years; duration 1.5 to 20 years, an average of 4.5 years; type of seizure in accordance with the International Classification of Seizures: the whole body 6 cases of sexual seizures, complicated partial seizures in 4 cases, simple partial seizures in 1 case, partial seizures secondary to systemic seizures in 1 case; both long-term use of antiepileptic drugs, clinically diagnosed as refractory epilepsy, a clear surgical adaptation All patients underwent preoperative 2 to 5 times EEG or dynamic