【摘 要】
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In his watershed 1896 essay The Tall Office Building Artistically Considered,protomode architect Louis Sullivan famously declared that ‘form follows function.C
【机 构】
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Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory,USA
论文部分内容阅读
In his watershed 1896 essay The Tall Office Building Artistically Considered,protomode architect Louis Sullivan famously declared that ‘form follows function.Could this concept also hold true in biology? Have cells,through evolutionary optimization,adopted a 3D architecture (‘form) that reflects their function? Or,to keep with the architectural metaphor,how does ‘form
elate to the cells ‘intended function or purpose? Is there an ultrastructural signature that reflects the ‘constraints and requirements of a cells function in its specific spatial and temporal context?
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