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原发性高血压(EH)的病因和发病机制十分复杂。内皮素(ET)是迄今所知体内最强的缩血管物质,降钙素基因相关肽(CGRP)是体内最强的扩张血管物质,两者对维持正常血压起着重要的作用。本文观察了99例EH患者的血浆ET和CGRP含量变化以及硝苯地平缓释剂对其的影响。1 对象与方法1.1
Etiology and pathogenesis of essential hypertension (EH) is very complicated. Endothelin (ET) is by far the strongest vasoconstrictor substance in the body, and calcitonin gene-related peptide (CGRP) is the strongest dilated blood vessel in the body, both of which play an important role in maintaining normal blood pressure. This article observed 99 cases of EH patients with plasma ET and CGRP content changes and the effect of nifedipine sustained-release agent on it. 1 objects and methods 1.1