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目的了解本地区不同年龄组妇女就诊人群人乳头瘤病毒(HPV)13种高危型感染情况,以及与细菌性阴道病相关性,为子宫颈癌防治提供依据。方法对3150例妇科就诊人群采集宫颈分泌物,应用实时荧光多重核酸基因扩增检测技术进行13种高危型HPV感染检测,其中419例同时用Amsel法进行细菌性阴道炎(BV)检测,统计比较不同年龄组之间,以及BV阳性组高危型HPV感染情况。结果 3150例就诊人群中,高危型HPV感染总阳性率为27.9%,随着年龄增长,高危型HPV感染率呈增高趋势,70岁以后下降;BV阳性组高危型HPV感染率34.5%,明显高于BV阴性组。结论 30岁到60岁妇女为高危型HPV感染高发人群,BV患者高危型HPV感染率明显增高。
Objective To understand the high risk infection of human papillomavirus (HPV) in women of different age groups in this area, as well as the correlation with bacterial vaginosis and to provide evidence for the prevention and treatment of cervical cancer. Methods Cervical secretions were collected from 3150 gynecological patients and 13 high-risk HPV infections were detected by real-time fluorescent multiplex nucleic acid amplification assay. Among them, 419 cases were tested for bacterial vaginosis by Amsel’s method. Statistical comparison Different age groups, as well as BV-positive group of high-risk HPV infection. Results The total positive rate of high-risk HPV infection was 27.9% in 3150 treatment groups. With the increase of age, the prevalence of high-risk HPV infection tended to increase and decreased after 70 years old. The high-risk HPV infection rate of BV positive patients was 34.5% In BV negative group. Conclusions Women aged 30 to 60 years old are high-risk HPV infection, and the high-risk HPV infection rate is significantly higher in patients with BV.