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目的:探讨甲状腺滤泡癌样肾细胞癌的诊断、治疗及预后。方法:回顾分析2009年1月~2015年8月期间收治的5例病理诊断为甲状腺滤泡癌样肾细胞癌患者的临床表现、诊断方法、手术方式、病理资料及预后情况等。结果:5例甲状腺滤泡癌样肾细胞癌患者中,男1例,女4例,年龄20~55岁,平均39岁。病变均位于单侧肾脏,左肾3例,右肾2例。B超显示偏强回声结节,CT显示不同程度强化。肿瘤最大径为2.5~4.0cm,平均3.2cm。TNM分期:T1N0M04例,T1N1M01例。5例患者均行手术治疗,其中根治性肾切除术3例,保留肾单位手术2例。术后均获随访,随访3~82个月,平均49个月,均未见肿瘤复发和转移。结论:甲状腺滤泡癌样肾细胞癌是肾细胞癌中的一种罕见类型,预后较好。影像学检查对其早期诊断有重要价值,最终确诊需要病理学检查。手术治疗为首选治疗方法。
Objective: To investigate the diagnosis, treatment and prognosis of thyroid follicular carcinoma-like renal cell carcinoma. Methods: The clinical manifestations, diagnostic methods, surgical methods, pathological data and prognosis of 5 patients with thyroid follicular carcinoma were analyzed retrospectively from January 2009 to August 2015. Results: Among 5 cases of thyroid follicular carcinoma-like renal cell carcinoma, there were 1 males and 4 females, aged from 20 to 55 years, with an average of 39 years. Lesions were located in the unilateral kidney, left kidney in 3 cases, 2 cases of right kidney. B ultrasound showed strong echo nodules, CT showed varying degrees of enhancement. The largest diameter of tumor was 2.5 ~ 4.0cm, with an average of 3.2cm. TNM staging: T1N0M04 cases, T1N1M01 cases. Five patients underwent surgical treatment, including radical nephrectomy in 3 cases and nephron union in 2 cases. All patients were followed up for 3 to 82 months (average 49 months). Neither tumor recurrence nor metastasis was observed. Conclusions: Thyroid follicular carcinoma-like renal cell carcinoma is a rare type of renal cell carcinoma with a good prognosis. Imaging examination of its early diagnosis of great value, the final diagnosis requires pathological examination. Surgical treatment is the preferred treatment.