目的 :观察米索前列醇 (米索 )在妊娠高血压综合征 (妊高征 )患者产后出血的影响。方法 :对 6 1例妊娠高血压综合征患者在胎儿娩出后立即给予米索前列醇 40 0μg口服 (米索组 ) ,6 0例同期妊娠高血压综合征患者在胎儿娩出后立即臀部肌肉注射缩宫素 2 0 IU (缩宫素组 )。观察两组患者的第三产程时间、产后出血量、产后出血发生率以及米索组使用药物前后的血压变化。结果 :1两组患者的年龄、孕周、产次、轻、中、重度妊高征所占的比例、产前及产时处理、新生儿体重相比 ,差异无显著性 (P>0 .0 5 ) ,二组有可比性。2米索组 :第三产程时间 7.2 8± 3.2 3min,产后出血量 172 .4± 93.2m l,产后出血发生率 4.9% (3/6 1)。缩宫素组 :第三产程时间 9.5 3± 3.42 min,产后出血量 2 78.5± 12 1.3ml,产后出血发生率 2 3.3% (14/6 0 )。二组相比米索组第三产程时间、产后出血量及产后出血发生率皆明显少于缩宫素组 (P<0 .0 1)。36 1例服用米索的患者服药前收缩压 2 0 .2± 2 .1k Pa,舒张压 12 .9± 1.86 k Pa,服药后收缩压 19.4± 1.99k Pa,舒张压12 .6± 1.72 k Pa。服药后收缩压和舒张压皆有所下降 ,但差异无显著性 (P>0 .0 5 )。 4服用米索组 3例出现恶心及呕吐。皆为一过性 ,无需特殊处理。结论 :妊高征患者胎? Objective: To observe the effect of misoprostol (misoprostol) on postpartum hemorrhage in patients with pregnancy induced hypertension (PIH). Methods: Sixty patients with pregnancy induced hypertension (BPH) were given oral misoprostol 40 μg (misoprostol) immediately after the delivery of the fetus, and 60 patients with synchronous pregnancy induced hypertension were injected intramuscularly immediately after delivery Uterine hormone 2 0 IU (oxytocin group). The duration of the third stage of labor, the amount of postpartum hemorrhage, the incidence of postpartum hemorrhage and the changes of blood pressure before and after using the drug in the misoprostol group were observed. Results: 1 There was no significant difference in age, gestational age, parity, proportion of mild, moderate and severe pregnancy-induced hypertension among the two groups, prenatal and intrapartum birth weight, and body weight of neonates (P> 0.05). 0 5), the two groups are comparable. 2 Misoprostol: The duration of the third stage of labor was 7.28 ± 3.2min, the postpartum hemorrhage was 172.4 ± 93.2m, and the incidence of postpartum hemorrhage was 4.9% (3/6 1). Oxytocin group: the third stage of labor 9.5 3 ± 3.42 min, postpartum hemorrhage 2 78.5 ± 12 1.3ml, the incidence of postpartum hemorrhage 23.3% (14/60). Two groups compared with misoprostol in the third stage of labor time, postpartum hemorrhage and postpartum hemorrhage were significantly less than oxytocin group (P <0.01). 36 One patient taking misoprostol had a systolic blood pressure of 20.2 ± 2.1kPa and a diastolic pressure of 12.9 ± 1.86kPa after taking medication, systolic blood pressure of 19.4 ± 1.99kPa and diastolic blood pressure of 12.6 ± 1.72k Pa. Systolic blood pressure and diastolic blood pressure decreased after taking medicine, but the difference was not significant (P> 0.05). 3 taking misoprostol 3 cases of nausea and vomiting. Are transient, without special treatment. Conclusion: PIH patients with fetal?