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目的通过对妇科患者泌尿系感染的细菌培养结果分布情况及药敏应用进行统计分析,为合理用药提供实验室数据支持。方法 110例尿路感染患者作为研究对象,取中段尿进行细菌培养,对培养出的细菌进行鉴定以及相对应的药物敏感度试验,统计出不同病原菌的分布情况以及相应耐药性情况。结果 110例标本通过细菌培养检测出88例,阳性率为80.0%。革兰染色分类其中革兰阴性杆菌62例,所占比例为70.5%。革兰阳性球菌26例,所占比例为29.5%。药物敏感度试验:革兰阴性杆菌对氨苄西林、左氧氟沙星、氨苄青霉素耐药率较高,对碳青霉烯类抗菌药物较敏感,选用经济头孢菌素等药物进行治疗具有敏感性;革兰阳性球菌对对左氧氟沙星、青霉素、氨苄西林的耐药率较高,万古霉素100.0%敏感。作为革兰阳性球菌对氨卡青霉素药物敏感性不足,三代头孢菌素敏感度表现中等。结论妇科泌尿系统感染的主要致病菌是革兰阴性杆菌,临床治疗需根据不同类型细菌有针对性选用敏感性较好的抗生素。
OBJECTIVE: To provide a laboratory data support for rational drug use by analyzing the distribution of bacterial culture results and drug susceptibility in gynecological patients with urinary tract infection. Methods One hundred and ten cases of urinary tract infection were selected as the research object. The middle part of the urine was used for bacterial culture. The bacteria were identified and the corresponding drug susceptibility tests were conducted. The distribution of different pathogens and the corresponding drug resistance were calculated. Results In 110 cases, 88 cases were detected by bacterial culture, the positive rate was 80.0%. Gram stain classification which Gram-negative bacilli 62 cases, accounting for 70.5%. Gram-positive cocci in 26 cases, accounting for 29.5%. Drug susceptibility test: Gram-negative bacilli ampicillin, levofloxacin, ampicillin resistance rate is higher, more sensitive to carbapenem antibiotics, the choice of economic cephalosporins and other drugs for treatment is sensitive; Gram-positive Cocci of levofloxacin, penicillin, ampicillin resistance rate is higher, vancomycin 100.0% sensitive. As gram-positive cocci ampicillin drug sensitivity, third-generation cephalosporins moderate sensitivity. Conclusions The main pathogens of gynecological urinary tract infection are Gram-negative bacilli. According to the different types of bacteria, clinical treatment should be conducted with sensitive antibiotics.