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目的总结丹参酮注射液联合大剂量甲钴胺治疗糖尿病足的效果,为糖尿病足治疗工作提供参考。方法选择该院2013年1月—2017年2月收治治疗的120例糖尿病足患者,分为丹参酮注射液治疗的对照组以及丹参酮注射液联合大剂量甲钴胺治疗的实验组,两组患者例数一致。对比两组糖尿病足患者的治疗总有效率以及生化指标变化情况。结果实验组糖尿病足患者的治疗总有效率90%明显高于对照组70%,经统计学计算差异有统计学意义(P<0.05)。另外,治疗前组间生化指标对比差异无统计学意义(P>0.05),治疗后实验组均优于治疗前以及对照组(P<0.05)。结论对糖尿病足患者而言,相对于丹参酮注射液单一治疗,联合大剂量甲钴胺治疗整体疗效更为显著,具有临床推广实施价值。
Objective To summarize the effect of tanshinone injection combined with high-dose mecobalamin in the treatment of diabetic foot, and provide a reference for the treatment of diabetic foot. Methods A total of 120 patients with diabetic foot admitted to our hospital from January 2013 to February 2017 were divided into experimental group treated with tanshinone injection and tanshinone injection combined with high dose mecobalamin. The patients in two groups The same number. Compare the total effective rate of two groups of patients with diabetic foot and the change of biochemical indexes. Results The total effective rate of 90% of patients with diabetic foot in the experimental group was significantly higher than that of the control group (70%). The difference was statistically significant (P <0.05). In addition, there was no significant difference in biochemical indexes between the two groups before treatment (P> 0.05). After treatment, the experimental groups were better than those before treatment and the control group (P <0.05). Conclusion Compared with tanshinone single injection treatment, the overall curative effect of mecobalamin in combination with high dose of mecobalamin is more significant in patients with diabetic foot, which has the value of clinical promotion.