论文部分内容阅读
VDR早期和恢复期患儿甲状腺和甲状旁腺分泌功能与正常婴幼儿相比有显著性变化:血T_3和iPTH浓度均明显增高,差异有显著性(P<0.05),而恢复期患儿以血T_4浓度明显增高为显著特点(P<0.05)。婴幼儿在维生素D不缺乏时仍可发生VDR,其发病关键可能在于维生素D活性代谢产物缺乏,特别是1,25(OH)_2D_3的缺乏。另外,T_4/T_3和iPTH/CT分泌比值在对VDR的深入研究中可能有重要临床价值。
The secretion of thyroid and parathyroid in children with early and recovery VDR had significant changes compared with normal infants: blood T_3 and iPTH concentrations were significantly increased, the difference was significant (P <0.05), while the recovery of children with Blood T 4 concentration was significantly increased (P <0.05). Infants and young children can still occur in the absence of vitamin D VDR may occur, the key may be the lack of active metabolites of vitamin D, especially the lack of 1,25 (OH) _2D_3. In addition, the ratio of T_4 / T_3 and iPTH / CT secretion may have important clinical value in the further study of VDR.