1905年Lazarus首次报道了嗜硷性粒细胞白血病。Doan等于1941年报告了4例,并对原发性和继发性作了区别。1948年Chevallier和1951年Marinoni分别提出原发性嗜硷性粒细胞白血病的诊断标准。其治疗与急性粒细胞白血病、慢粒急变相同,但效果较差,常因心力衰竭伴支气管肺炎,齿槽内出血而死亡。 Lazarus first reported in 1905 basophilic leukemia. Doan et al. Reported 4 cases in 1941 and made a distinction between primary and secondary. Chevallier in 1948 and Marinoni in 1951, respectively, the diagnosis of primary allergic leukemia criteria. The treatment of acute myeloid leukemia, chronic myogenic change the same, but less effective, often due to heart failure with bronchial pneumonia, alveolar hemorrhage and death.