一项临床试验日前表明,一种基因编码技术对于人类而言是安全且有效的。这是研究人员第一次使用一种名为锌指核酸酶(ZFN)的酶瞄准并破坏了12名艾滋病病毒(HIV)携带者免疫细胞中的一种基因,从而增强了他们抵抗病毒的能力。该项研究成果发表在3月6日出版的《新英格兰医学杂志》上。美国加利福尼亚州杜瓦迪市希望之城国家医学中心贝克曼研究所分子生物学家John Rossi说:“这是HIV基因疗法的第一个重大进步,因为它证明了‘柏林病人’Timothy Brown如何远离HIV。” A clinical trial recently showed that a genetic coding technique is safe and effective for humans. This is the first time that researchers have targeted and destroyed one of 12 HIV-infected immune cells using an enzyme called zinc finger nuclease (ZFN), thereby enhancing their resistance to the virus . The research was published in the New England Journal of Medicine on March 6. John Rossi, molecular biologist at the Beckman Institute for National Medical Center, Hope City, Dovald, CA, USA, said: “This is the first major step forward in HIV gene therapy because it demonstrates how Timothy Brown, a ’Patient of Berlin’ Stay away from HIV. ”