论文部分内容阅读
报导发生在Wistar大鼠的一例自发性子宫内膜间质细胞肉瘤。该瘤生长在一侧子宫,呈不规则的卵圆形,其大小为l·b·h,cm:8×6×3,表面光滑,质地柔韧,呈淡黄色鱼肉状,有的部位呈局灶状棕褐色。光镜下可见肿瘤由分化较低的圆形或卵圆形细胞构成,瘤细胞呈致密而均匀弥漫排列。胞核增大,呈圆形或椭圆形,多数瘤细胞核空泡变性。可见核分裂相,大约为10个/10个高倍视野。银染色瘤细胞呈网篮状排列。肿瘤向肌层浸润,呈蔓延生长。电镜下瘤细胞核肿大,且不规则,胞浆内的粗面内质网扩张,细胞器明显减少。此瘤来源于间胚叶的肿瘤。
A case of spontaneous endometrial stromal cell sarcoma was reported in Wistar rats. The tumor grew on one side of the uterus, irregular oval shape, the size of l · b · h, cm: 8 × 6 × 3, smooth surface, soft texture, pale yellow fish-shaped, and some sites were Board Kitchen-like tan. Light microscopic tumor can be seen from the less differentiated round or oval cells, tumor cells were dense and uniform diffuse arrangement. Nuclei increased, round or oval, most of the tumor cell vacuolar degeneration. Visible nuclear fission phase, about 10/10 high power field. Silver staining tumor cells were basket-like arrangement. Tumor invasion to the muscle layer, was spread growth. Electron microscope tumor nuclei swollen, and irregular, intracytoplasmic rough endoplasmic reticulum dilated, organelles significantly reduced. This tumor is derived from mesodermal tumor.