〔答〕内热原是细菌内毒素及其它外源性致热原进入机体内,经过使细胞活化产生一种对热不稳定的新蛋白质,能透入中枢神经,作用于视前区丘脑下部的前部,引起前列腺素PGE的合成和释放,致机体发热,这种产生的新蛋白质称为内热原. 当内热原出现时,外热原已从血液循环中消失,所以外热原不是直接引起发热的因素.阿司匹林等解热镇痛剂能阻断PGE的生物合成,因此,能明显 [Answer] Endogenous endotoxin is a bacterial endotoxin and other exogenous pyrogens that enter the body. After activation of the cell, it produces a heat-labile new protein that penetrates into the central nervous system and acts on the hypothalamus in the preoptic area. In the anterior part, the prostaglandin PGE is synthesized and released, causing the body to produce fever. The new protein produced is called endopyreogen. When the pyrogen is present, the exogenous pyrogen has disappeared from the blood circulation, so the exogenous pyrogen is not directly induced. Factors of fever. Antipyretic analgesics such as aspirin can block the biosynthesis of PGE and therefore can be significantly