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目的:探讨青春期功能失调性子宫出血(青春期功血)的后续治疗方法。方法:将90例青春期功血患者分为两组:A组在止血后第1次月经来潮的第2天开始服用戊酸雌二醇片1mg,每日1次,3个月为1个疗程,同时观察排卵情况(BBT);B组仅观察排卵情况(BBT)。结果:A组45例功血患者服用小剂量雌激素第1疗程后BBT双相者8例,占17.8%;第2疗程后BBT双相者27例,占60.0%;第3疗程后BBT双相者38例,占84.4%。B组45例第1月后BBT双相者0例;第2月后BBT双相者3例,占6.7%;第3月后BBT双相者5例,占11.1%。两组治疗3个月后的排卵情况经统计学处理,P<0.01,差异有统计学意义。结论:小剂量雌激素促排卵效果肯定,无明显不良作用,患者顺应性好,可用于青春期功血患者的后续治疗。
Objective: To explore the follow-up treatment of adolescent dysfunctional uterine bleeding (adolescent dysfunctional uterine bleeding). Methods: Ninety adolescent dysfunctional uterine bleeding patients were divided into two groups: Group A started taking estradiol valerate 1mg once daily and 3 months as a course of treatment on the second day of the first menstruation after hemostasis , While observing ovulation (BBT); Group B only observed ovulation (BBT). Results: A total of 45 cases of dysfunctional uterine bleeding in group A took 8 patients (17.8%) with BBT biphasic after the first course of treatment, and 27 cases (60.0%) were treated with BBT after the second course. BBT Phase 38 cases, accounting for 84.4%. There were 0 cases of BBT bipolar in 45 cases of group B after 1 month, 3 cases of BBT bipolar in 2 months, accounting for 6.7%, and 5 cases of BBT in 3 months, accounting for 11.1%. Ovulation 3 months after treatment in both groups by statistical analysis, P <0.01, the difference was statistically significant. Conclusion: The effect of small dose of estrogen on promoting ovulation is affirmative, with no obvious adverse effect. The patient has good compliance and can be used for follow-up treatment of adolescent dysfunctional uterine bleeding.