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目的调查江苏省人与动物发热伴血小板减少综合征布尼亚病毒(SFTSV)血清流行病学情况,为控制疫情提供流行病学线索。方法 2010年7-11月在江苏省南京江宁区、溧水县,常州溧阳市,无锡宜兴市,淮安盱眙县和连云港东海县共采集2853份血清,其中人血清1922份、动物(犬、羊、猪、牛、鹅、鼠和鸡)血清931份,运用双抗原夹心ELISA法检测血清中SFTSV总抗体,并进行不同地区SFTSV总抗体阳性率比较。结果本次调查2853份血清样本中SFTSV总抗体阳性血清121份,阳性率为4.24%,提示江苏省存在SFTSV的流行。在7种被调查的动物样本中,5种动物(犬、羊、牛、猪、鸡)血清样本SFTSV总抗体阳性,阳性率分别为6.40%、57.14%、31.82%、5.33%和0.98%;人血清中SFTSV总抗体阳性率为0.94%。血清中SFTSV总抗体阳性率存在地区差异。人群与动物SFTSV血清总抗体阳性率存在正相关关系。结论江苏省是SFTSV的流行区域,需加强SFTSV的预防意识及诊断能力。
Objective To investigate the serological epidemiology of feverish with thrombocytopenic syndrome Bunyavirus (SFTSV) in Jiangsu Province and to provide epidemiological clues for controlling the epidemic. Methods A total of 2853 serum samples were collected from Jiangning District, Lishui County, Liyang City, Changzhou, Liyang City, Changzhou, Yixing City, Wuxi, Xuyi County and Donghai County, Lianyungang from July to November in 2010, including 1922 human serum samples, 931 serum of pigs, cattle, geese, rats and chickens). The total antibody to SFTSV in serum was detected by double antigen sandwich ELISA and the positive rate of total SFTSV antibody in different regions was compared. Results The total number of SFTSV positive sera in 2853 serum samples from this survey was 121, with a positive rate of 4.24%, suggesting that there was a prevalence of SFTSV in Jiangsu Province. Among the seven animal samples tested, the total SFTSV antibody positive rates of the five kinds of animals (dogs, sheep, cattle, pigs and chickens) were 6.40%, 57.14%, 31.82%, 5.33% and 0.98%, respectively. The positive rate of SFTSV total antibody in human serum was 0.94%. Serum SFTSV total antibody positive rate of regional differences. Population and animal SFTSV serum total positive rate of positive correlation. Conclusion Jiangsu Province is the endemic area of SFTSV. It is necessary to strengthen the awareness of prevention and diagnosis of SFTSV.