通过加入催化剂量的表面活性剂,在氯化钯催化的水介质中实现了3,5-二氯苯甲酸、2溴-4-甲-基吡啶与四苯硼钠的Suzuki偶联反应,并且探讨了表面活性剂的用量、反应温度等条件的影响。在有机溶剂-水介质中,二溴芳烃、三溴芳烃与四苯硼钠反应时,0.05 mmol的苄基三乙基氯化铵的加入可以使相同产物产率下的氯化钯用量由3%减少至1%。 Suzuki coupling of 3,5-dichlorobenzoic acid, 2-bromo-4-methyl-pyridine and sodium tetraphenylborate was achieved in a palladium chloride catalyzed aqueous medium by adding a catalytic amount of surfactant and The effects of the amount of surfactant, reaction temperature and other conditions were discussed. In the organic solvent - aqueous medium, dibromoarenes, tribromoarenes and tetraphenylboron sodium reaction, 0.05 mmol of benzyl triethylammonium chloride can be added in the same product yield of palladium chloride from 3 % Reduced to 1%.