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目的:研究颈动脉粥样硬化斑块发生的危险因素及与脑梗死的关系。方法:选取2013年7月到2014年7月我院收治的脑梗死患者120例(研究组),另选取非脑梗死患者或者健康体检者120例(对照组),对所有入选者实施颈部血管超声检查,并检测其血糖、血浆纤维蛋白原和血脂,比较两组颈动脉粥样硬化斑块的数目、部位、颈动脉内径并分析脑梗死危险因素。结果:研究组斑块检出率和斑块数显著高于对照组,两组比较差异具有统计学意义(P<0.05);颈总动脉内径显著小于对照组,两组比较差异具有统计学意义(P<0.05);斑块存在于颈总动脉者最多,且与脑梗死部位存在同侧相关性(P<0.05);研究组年龄、高血压、糖尿病和血脂、纤维蛋白原(FIB)也显著高于对照组,两组比较差异具有统计学意义(P<0.05)。结论:颈动脉粥样硬化斑块发生和脑梗死存在密切关系,年龄、糖尿病、高血压、FIB和血脂均是其危险因素。
Objective: To study the risk factors of carotid atherosclerosis plaque and its relationship with cerebral infarction. Methods: A total of 120 patients with cerebral infarction (study group) admitted to our hospital from July 2013 to July 2014 were enrolled in this study. 120 non-cerebral infarction patients or 120 healthy people (control group) The blood vessels were ultrasonographed and their blood glucose, plasma fibrinogen and blood lipids were measured. The number of carotid atherosclerotic plaque, the location of the carotid artery and the risk factors of cerebral infarction were compared between the two groups. Results: The detection rate of plaque and the number of plaque in the study group were significantly higher than those in the control group (P <0.05). The diameter of the common carotid artery was significantly smaller than that in the control group. There was significant difference between the two groups (P <0.05). The plaque existed in the common carotid arteries and had the same ipsilateral correlation with cerebral infarction (P <0.05). The age, hypertension, diabetes mellitus and serum lipids, fibrinogen (FIB) Significantly higher than the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion: The occurrence of carotid atherosclerosis is closely related to cerebral infarction. Age, diabetes, hypertension, FIB and lipids are the risk factors.