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糖尿病慢性并发症主要为大血管病变(心脏病、高血压、脑血管意外及下肢血管病变)、微血管病变(视网膜病变、肾脏病变)和神经病变等。慢性并发症的病理基础为血管病变,肺脏是微血管极为丰富的器官之一,近年来越来越多的研究发现亦除传统的靶器官之外,肺脏亦成为糖尿病损害的靶器官~([1])。本研究通过观察60例2型糖尿病患者胰岛素强化治疗前后肺功能的变化,探讨2型糖尿病患者肺功能的改变与胰岛素抵抗的关系。
Chronic complications of diabetes are mainly macrovascular disease (heart disease, hypertension, cerebrovascular accident and lower extremity vascular disease), microangiopathy (retinopathy, nephropathy) and neuropathy. The pathological basis of chronic complications is vascular disease. The lungs are one of the most abundant organs in the blood vessels. In recent years, more and more studies have found that besides the traditional target organs, the lungs also become the target organs for the damage of diabetes ([1 ]). In this study, we observed the changes of lung function in 60 patients with type 2 diabetes before and after intensive insulin therapy to investigate the relationship between the changes of lung function and insulin resistance in type 2 diabetic patients.