糖尿病患者因胰岛素所致低血糖反应的治疗通常是口服糖、静脉注射葡萄糖或肌内、皮下注射胰升糖素(glucagon)。但病人昏迷、躁动或抽搐时这些治疗就很困难。作者研究鼻腔喷雾胰升糖素对血糖的影响。以6名健康志愿者为对照组,平均年龄为30岁。6例胰岛素依赖型(Ⅰ型)糖尿病患者平均年龄为26.6岁。病人组先停用胰岛素12h 以上。试验前于受试者前臂浅静脉插入导管以便注射胰岛素及采血,临用前用1%去氧胆酸盐和蒸馏水配制胰升糖素溶液。先用正规胰岛素使血糖控制至正常范围(5.5～7.7mmol/L)。试验开始先注射胰岛素0.2U/kg,当血糖降至3.8～5.5mmol/L 时,注射0.1U/kg,每 The treatment of insulin-induced hypoglycemia in diabetic patients is usually oral glucose, intravenous glucose or intramuscular injection of glucagon subcutaneously. However, these treatments are difficult when the patient coma, agitation or convulsions. The authors investigated the effect of nasal spray glucagon on blood glucose. Six healthy volunteers as control group, with an average age of 30 years. Six patients with insulin-dependent type I diabetes had an average age of 26.6 years. Patients in the group to disable insulin for more than 12h. Prior to the test, a catheter was inserted into the superficial forearm of the forearm for injection of insulin and blood sampling. The glucagon solution was formulated with 1% deoxycholate and distilled water just before use. First with regular insulin blood glucose control to the normal range (5.5 ~ 7.7mmol / L). At the beginning of the experiment, insulin 0.2 U / kg was injected. When blood glucose dropped to 3.8-5.5 mmol / L, 0.1 U / kg