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目的研究苯那普利对早期高血压心室肥厚和左心舒张功能的影响。方法血浆肾素活性、血管紧张素Ⅱ及醛固酮的含量在治疗前后被监测。左心室肌重及心舒张功能用彩色多普勒心动仪测定。结果经治疗３到４个月，血浆肾素、血管紧张素Ⅱ及醛固酮的含量降低。室间隔厚度（ＩＶＳＴ）、左室后壁厚度（ＬＶＰＷ）、左室质量（ＬＶＭ）缩小。心房收缩峰速（Ａ）和快速充盈峰速（Ｅ）之比降低。心室舒张平均速和峰速值增加。心室收缩功能指标如ＳＶ，ＥＦ和ＦＳ无变化。结论经苯那普利治疗后血压、心室质量及左心舒张功能指标有改善
Objective To investigate the effects of benazepril on early hypertensive ventricular hypertrophy and left ventricular diastolic function. Methods Plasma renin activity, angiotensin II and aldosterone levels were monitored before and after treatment. Left ventricular muscle mass and diastolic function were measured by color Doppler echocardiography. Results After 3 to 4 months of treatment, the levels of plasma renin, angiotensin II and aldosterone were decreased. Interventricular septum thickness (IVST), left ventricular posterior wall thickness (LVPW), left ventricular mass (LVM) decreased. Atrial contraction peak velocity (A) and rapid filling peak velocity (E) ratio decreased. Ventricular diastolic mean velocity and peak velocity increased. Ventricular systolic function indicators such as SV, EF and FS did not change. Conclusion After treatment with benazepril, blood pressure, ventricular mass and left ventricular diastolic function improved