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试自乙型肝炎病毒血清标志(HBVM)阳性胎盘提取特异转移因子(PSTF)治疗慢性乙型肝炎(慢性活动型167例、慢性迁延型16例、慢性活动性肝炎有硬变趋势者11例、肝炎肝硬变6例)200例,平均疗程82天,来见毒副反应,临床治愈率83.0％、进步11.0％、无效6.0％;近期HBsAg、HBeAg阴转率为9.9％和32.8％;出院后平均随访5 1/2月,病情波动者13.9％,出院时进步和无效者,复查时转临床治愈分别为40.0％和50.0％。本文认为PSTF对慢乙肝有较好疗效,值得进一步研究提高。
In this study, chronic hepatitis B (167 cases of chronic active type, 16 cases of chronic persistent type, 11 cases of chronic active hepatitis with cirrhosis) were treated with HBVM positive placenta extract specific transfer factor (PSTF) Hepatitis cirrhosis in 6 cases) 200 cases, the average course of 82 days, to see toxic and side effects, the clinical cure rate was 83.0%, 11.0% improvement, ineffective 6.0%; recent HBsAg, HBeAg negative conversion rate was 9.9% and 32.8% After a mean follow-up of 51/2 months, the condition was fluctuated by 13.9%, and those who were discharged at the time of discharge were ineffective. The clinical cure rates at the time of review were 40.0% and 50.0% respectively. This article believes that PSTF has a good effect on chronic hepatitis B, it is worth further study and improvement.