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人类甲型和乙型肝炎病毒所致感染已可用各种血清学和酶的标志检查加以确定,目前有60~90%输血后的肝炎病人在血清学上均未发现与上述二种肝炎有关的病毒,巨细胞病毒和E-B病毒显然亦与这些病例无关。人们推测可能存在另一种非甲非乙型肝炎病毒。本文研究了一些患急性或慢性非甲非乙型肝炎病人的血液以探查是否存在一种可传染给猩猩的传播因子。资料和方法 4例急性或慢性非甲非乙型输血后肝炎(PTH)患者和1例曾触发二起PTH献血员的血浆或血清由静脉接种于5头黑猩猩,接种量自3~75毫升不等。输血后肝炎的诊断依据是输血后2~26周中,ALT(丙氨酸转氨酶)上升至正常限值之2 1/2倍(112Iu/升),第二次复查(间隔至少1周)超过正
Infection with human Hepatitis A and Hepatitis B virus has been confirmed by various serological and enzymatic marker tests. Currently, 60 to 90% of post-transfusion hepatitis patients are not serologically found to be associated with the above two types of hepatitis Viruses, cytomegalovirus and Epstein-Barr virus are clearly also unrelated to these cases. There is speculation that there may be another non-A, non-B hepatitis virus. This article examines the blood of some patients with acute or chronic non-A, non-B hepatitis to investigate the presence of a transmission agent that can be transmitted to orangutans. Materials and Methods Four patients with acute or chronic non-A, B hepatitis A (PTH) and one plasma or serum that had triggered two PTH donors were inoculated intravenously to five chimpanzees from 3 to 75 mL Wait. Hepatitis B after transfusion is diagnosed by ALT (alanine aminotransferase) up to 2 1/2 times the normal limit (112Iu / liter) 2 to 26 weeks after transfusion, the second review (interval of at least 1 week) over positive