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目的:探讨炎症性肌纤维母细胞瘤(IMT)在口腔颌面部的临床表现及治疗方法。方法:回顾总结2007—2011年期间诊治的8例颌面部IMT患者,分析其临床资料及治疗方法。结果:口腔颌面部炎症性肌纤维母细胞瘤肉眼观均为实性肿物,呈浸润性生长,与周围软组织黏连,无明显包膜。肿瘤镜检主要有梭形细胞型和黏液血管型2种组织学形态。除1例术后失访外,其余患者随访1～3a,情况稳定,未见局部复发或远处转移。结论:IMT是一种少见的间叶性肿瘤,多见于儿童和青壮年,罕见于头颈部,具有局部侵袭性和复发等低度恶性或交界瘤特点,远处转移少见;手术切除是口腔颌面部IMT首选的治疗方法。
Objective: To investigate the clinical manifestations and treatment of inflammatory myofibroblastic tumor (IMT) in oral and maxillofacial region. Methods: Eight cases of maxillofacial IMT patients diagnosed and treated during 2007-2011 were reviewed and summarized. Clinical data and treatment methods were analyzed. Results: Oral and maxillofacial inflammatory myofibroblastic tumors were solid tumors in the macroscopic view, showing invasive growth, with the surrounding soft tissue adhesions, no significant capsule. Tumor microscopy mainly spindle cell type and mucus vascular 2 kinds of histological morphology. Except for one case of postoperative follow-up, the other patients were followed up for 1-3 years. The situation was stable and no local recurrence or distant metastasis was found. Conclusion: IMT is a rare mesenchymal tumor, more common in children and young adults, rare in the head and neck, with local invasion and recurrence of low-grade or borderline tumor characteristics, distant metastasis rare; surgical removal of the oral cavity Maxillofacial IMT preferred treatment.