According to the comprehensive study of the depositional sequence of the outcrop sections from Cretaceous to Tertiary of the Tarim Basin, and the analyses of the seismic sequence and drilling data,the strata of Cretaceous-Tertiary of the Tarim Basin can be subdivided into 30 3rd-order depositional sequences in the southweste depression and 22 3rd-order dpositional sequences in the northweste depression. This indicates that the 3rd-order sequences can not be correlated directly one by one because of their different tectonic settings and sedimentary environments. Whereas, based on the study of 2nd-order supersequence, the strata from Cretaceous to Tertiary can be divided into 4 supersequences and correlated isochronously in these two areas of the Tarim Basin.