1临床资料患者男,34岁。全身关节疼痛3年,肌无力、皮肤肿胀及变硬2个月。3年前,无明显诱因右踝关节肿痛,当地医院以“痛风”予激素治疗后(药名不详),症状好转,但停药后不久病情复发,且左踝关节、双肘、肩、腕、指关节等处相继出现肿痛,多次到当地医院诊治,疗效不佳。1年余前双侧膝关节出现肿痛,蹲 1 clinical data patient male, 34 years old. Systemic joint pain for 3 years, muscle weakness, skin swelling and hardening 2 months. 3 years ago, there was no obvious incentive for swelling and pain in the right ankle. After the local hospital treated with “gout” (the drug name is unknown), the symptoms improved, but the condition recurred shortly after drug withdrawal. The left ankle joint, Shoulder, wrist, knuckles and other places have appeared swelling and pain, many times to the local hospital for treatment, poor efficacy. More than 1 year before the bilateral knee swelling and squatting