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血栓形成在心血管疾病中,特别是急性心肌梗死(acute myocardial infarction,AMI)和不稳定型心绞痛(unstable angina,UA)的发病中所起的重要作用已被血管造影、血管镜和尸检证明。并且冠状动脉硬化性心脏病(CHD)患者血小板活化,凝血功能增强,纤溶功能减退,存在明显的血栓前状态,测定血小板表面CD62p的表达、血浆组织纤溶酶原激活物(t-PA)、纤溶酶原激活抑制物(PAI-1)及凝血4项有助于早期发现冠心病患者血栓前状态并以
The important role of thrombosis in the pathogenesis of cardiovascular diseases, especially acute myocardial infarction (AMI) and unstable angina (UA), has been demonstrated by angiography, angiography and autopsy. And in patients with coronary heart disease (CHD), platelet activation, coagulation enhancement and fibrinolysis were reduced. There was obvious prethrombotic state. The expression of CD62p on platelet surface and the expression of plasma tissue plasminogen activator (t-PA) , Plasminogen activator inhibitor (PAI-1) and coagulation 4 contribute to the early detection of prethrombosis in patients with coronary heart disease and to