非动脉炎性缺血性视神经病变或外伤性视神经病变患者经角膜电刺激的治疗效果

来源 :世界核心医学期刊文摘.眼科学分册 | 被引量 : 0次 | 上传用户:ZHANGYJ000
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Purpose:To determine whether transcorneal electrical stimulation(TES) can improve the visual function of patients with nonarteritic ischemic optic neuropathy(NAION) or traumatic optic neuropathy(TON) .Methods:Eight consecutive patients at the Osaka University Hospital were studied.TES(600-800 μ A,20 Hz,30 min) was applied once each to three eyes with NAION and to five eyes with TON,using a contact lens-type stimulating electrode.The primary outcome measurement was the change in visual acuity at 1 to 3 months after TES.An improvement in visual acuity was defined as a change of ≥ 0.3 log(minimum angle of resolution) (logMAR) units.The side effects of TES were also investigated.Results:After TES application,the visual acuity improved in two patients with NAION and in four patients with TON.Visual acuity did not worsen in any of the eyes.Only a mild superficial punctuate keratopathy was observed in all eyes immediately after TES,and it healed by the next day.Conclusions:Visual acuity can be improved after TES without major complications in some patients with NAION or TON.These results suggest that TES should be considered as a new treatment for eyes with optic neuropathy. Purpose: To determine whether transcorneal electrical stimulation (TES) can improve the visual function of patients with nonarteritic ischemic optic neuropathy (NAION) or traumatic optic neuropathy (TON). Methods: Eight consecutive patients at the Osaka University Hospital were studied. TES (600 -800 μA, 20 Hz, 30 min) was applied once each to three eyes with NAION and to five eyes with TON, using a contact lens-type stimulating electrode. The primary outcome measurement was the change in visual acuity at 1 to 3 months after TES.An improvement in visual acuity was defined as a change of ≥ 0.3 log (minimum angle of resolution) (logMAR) units. The side effects of TES were also investigated. Results: After TES application, the visual acuity improved in two patients with NAION and in four patients with TON. Visual acuity did not worsen in any of the eyes. On a mild superficial punctuate keratopathy was observed in all eyes immediately after TES, and it healed by the next day. Conclusions: Visual acuity ca n be improved after TES without major complications in some patients with NAION or TON. These results suggest that TES should be considered as a new treatment for eyes with optic neuropathy.
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