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目的研究子宫腺肌症并发双下肢深静脉血栓的病因。方法 353例因子宫腺肌症行手术治疗的患者作为实验组,355例因子宫内膜息肉行手术治疗的患者作为对照组。采用病例回顾性研究对比分析子宫腺肌症并发血栓的原因。结果实验室患者的血红蛋白(Hb)值为(109.07±1.31)g/L,糖类抗原125(CA125)值为(101.29±14.68)IU/L,D-二聚体值为(154.28±14.18)μg/L;对照组患者的Hb值为(120.86±1.09)g/L,CA125值为(50.09±13.61)IU/L,D-二聚体值为(153.81±10.98)μg/L。两组Hb、CA125水平比较差异有统计学意义(t=130.2、48.1,P<0.05),两组D-二聚体水平比较差异无统计学意义(t=0.5,P>0.05)。结论子宫腺肌症伴贫血和CA125升高,这两者可致血液形成高凝状态,促进双下肢血栓形成。
Objective To study the etiology of adenomyosis with double lower extremity deep venous thrombosis. Methods 353 cases of adenomyosis due to surgical treatment of patients as experimental group, 355 cases of endometrial polyps surgical treatment of patients as a control group. A retrospective case-by-case analysis of the causes of thrombosis in patients with adenomyosis. Results The hemoglobin (Hb) value of laboratory patients was (109.07 ± 1.31) g / L, the value of CA125 was (101.29 ± 14.68) IU / L and the value of D-dimer was (154.28 ± 14.18) μg / L. The control group had a Hb value of (120.86 ± 1.09) g / L, a CA125 value of (50.09 ± 13.61) IU / L and a D-dimer value of (153.81 ± 10.98) μg / L. The levels of Hb and CA125 were significantly different between the two groups (t = 130.2,48.1, P <0.05). There was no significant difference in D-dimer levels between the two groups (t = 0.5, P> 0.05). Conclusion Adenomyosis with anemia and elevated CA125, both of which lead to the formation of hypercoagulable state of blood to promote thrombosis of both lower extremities.