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目的比较分析甲氨蝶呤(MTX)联合米非司酮口服治疗与单剂量甲氨蝶呤口服治疗未破裂异位妊娠的效果。方法56名未破裂异位妊娠接受药物保守治疗的患者分为两组,A组31例接受MTX联合米非司酮口服治疗,B组25例接受单剂量甲氨蝶呤治疗,比较两组患者保守治疗成功率及并发症发生率。结果 A组保守治疗成功率高于B组(P<0.05),术后并发症发生率低于B组(P<0.05)。结论在未破裂异位妊娠的保守治疗中,采取MTX联合米非司酮口服治疗效果好于单剂量甲氨蝶呤治疗,且并发症发生率更低。
Objective To compare the efficacy of methotrexate (MTX) with mifepristone in oral treatment and oral methotrexate in the treatment of unruptured ectopic pregnancy. Methods Fifty-six patients with unruptured ectopic pregnancy who received conservative treatment were divided into two groups: 31 patients in group A received MTX combined with mifepristone orally, and 25 patients in group B received methotrexate in single dose. Patients in both groups Conservative treatment success rate and complication rate. Results The success rate of conservative treatment in group A was higher than that in group B (P <0.05). The incidence of postoperative complications was lower than that in group B (P <0.05). Conclusion In the conservative treatment of unruptured ectopic pregnancy, MTX combined with mifepristone oral treatment is better than single-dose methotrexate treatment, and the complication rate is lower.