背景:关于无症状绝经后女性中次要和(或)主要心电图(ECG)异常的流行率、发病率及其独立预后价值的资料少见。激素疗法对ECG的预后价值有无影响亦缺乏相关信息。目的:研究基线时的次要、主要ECG异常和新发ECG异常与长期心血管疾病发生率和死亡率的相关性。设计、机构和参与者:对女性健康倡议研究中的雌激素联合黄体酮亚组研究进行事后分析。 Background: There is a paucity of information on the prevalence, incidence and independent prognostic value of secondary and / or major electrocardiographic (ECG) abnormalities in asymptomatic postmenopausal women. Hormonal therapy has no effect on the prognostic value of ECG and also lacks relevant information. PURPOSE: To study the association of secondary, major ECG abnormalities and new-onset ECG abnormalities at baseline with long-term cardiovascular morbidity and mortality. DESIGN, INSTITUTIONS, AND PARTICIPANTS: Post hoc analysis of the estrogen plus progesterone subgroup study in the Women’s Health Initiative study.