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以大肠肠管长轴为纵轴在横、纵、水平三个相互垂直的方向上对大肠癌、腺瘤及自身正常粘膜组织取材和切片,随机确定视野,对腺体的体密度(Vvg)、表面积密度(Svg)、比表面(Rsvg)、平均自由程(λg)4个腺体参数和细胞核的体密度(Vvn)、表面积密度(Svn)、比表面(Rsvn)、核浆比(Rnp)、平均自由程(λ)、平均体积(v)、数密度(Nv)、平均曲度密度(Kv)、平均表面积(s)9个细胞核参数以及核基距及核胞顶距进行了测试。结果:从不同方向对大肠癌、腺瘤及正常组织取材对以上13个体视学参数和核基距的测试结果差异均无显著性;部分取材方向上核胞顶距测试结果的差异有显著性。结论:从横、纵、水平三个不同方向取材对Vvg、Svg、Rsvg、λg、Vvn、Svn、Rsvn、Rnp、λ、v、Nv、Kv、s这13个体视学参数及核基距的测试结果无显著影响;而对核胞顶距的测试结果有显著影响
Colorectal cancers, adenomas, and normal mucosal tissues were drawn and sectioned in the transverse, longitudinal, and horizontal directions perpendicular to each other along the long axis of the large intestine intestine, and the visual field was randomly determined to determine the body density (Vvg) of the glands. Surface Area Density (Svg), Specific Surface (Rsvg), Average Free Path (λg), 4 glandular parameters and cell nucleus volume density (Vvn), Surface Area Density (Svn), Specific Surface (Rsvn), Nucleoplasm ratio (Rnp) The average free path (λ), average volume (v), number density (Nv), average curvature density (Kv), average surface area (s), 9 nuclear parameters, and nuclear distance and nucleus pitch were tested. RESULTS: There were no significant differences in the detection results of the 13 above individual inspecting parameters and nuclear base distance from different directions on colorectal cancer, adenoma, and normal tissue; there was a significant difference in the results of the nuclear nucleocapsid test on the direction of partial acquisition. . Conclusion: The 13 visual parameters and nuclear distances of Vvg, Svg, Rsvg, λg, Vvn, Svn, Rsvn, Rnp, λ, v, Nv, Kv, s were obtained from three directions of horizontal, vertical and horizontal directions. No significant effect on test results; significant effect on test results of nucleon pitch