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应用传统分类法及Scheuer分类法观察213例慢性肝炎的肝穿病理切片,共260例次。结果显示,Scheuer分类法与传统分类法基本一致。但对反映病变程度,动态观察病情、指导治疗等方面优于传统分类法;其病理分级与病人血清胆红素(SB)、丙氨酸转氨酶(ALT)有关,与病毒复制关系不明显;分期与病人蛋白代谢、慢性肝病体征等有关。47例病人2次肝穿病理变化显示,其炎症活动度的恢复较纤维化恢复快。
The traditional classification and Scheuer classification were used to observe the pathology of liver biopsy in 213 patients with chronic hepatitis, 260 cases in total. The results show that the Scheuer taxonomy is basically the same as the traditional taxonomy. But it is better than the traditional classification in reflecting the degree of disease, dynamic observation of the disease, guiding treatment, etc. The pathological grade is related to the serum bilirubin (SB) and alanine aminotransferase (ALT), but not to the virus replication. And the patient’s protein metabolism, chronic liver disease signs and so on. Pathological changes of liver biopsy in 47 patients showed that the recovery of inflammatory activity was faster than that of fibrosis.