以HZSM-5沸石作催化剂,应用常压液-固相酯化反应合成了乙酸丁酯。考察了催化剂用量、醇酸比、反应温度和反应时间对酯产率的影响。适宜的反应条件为:催化剂用量为0.30g/mol正丁醇、正丁醇/乙酸=1∶1.05(mol比)、反应温度110～120℃、反应时间5小时,所得酯产率在63%以上。产物的红外光谱分析表明,HZSM-5沸石催化剂在合成乙酸丁酯的反应中具有高选择性。 HZSM-5 zeolite as a catalyst, the application of atmospheric pressure liquid-solid phase esterification reaction of butyl acetate. The effects of catalyst amount, alkyd ratio, reaction temperature and reaction time on the yield of ester were investigated. The optimum reaction conditions are as follows: the amount of catalyst is 0.30g / mol butanol, n-butanol / acetic acid = 1: 1.05, the reaction temperature is 110-120 ℃ and the reaction time is 5 hours. the above. Infrared spectrum analysis of the product showed that the HZSM-5 zeolite catalyst has high selectivity in the synthesis of butyl acetate.