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目的研究枸橼酸咖啡因联合NCPAP治疗早产儿频繁呼吸暂停的疗效。方法选取本院收治的62例早产儿频繁呼吸暂停患儿作为样本,将其随机均分为实验组与对照组。对照组患儿采用常规NCPAP方法治疗,实验组患儿采用枸橼酸咖啡因联合NCPAP治疗。治疗中,观察两组患儿并发症发生情况,治疗24h后,观察两组患儿呼吸暂停发生次数,判断治疗效果。结果对照组患儿治疗有效率77.42%,实验组患儿治疗有效率96.77%,后者优势显著(P<0.05)。实验组患儿在心动过速(3.22%)与血糖异常(6.45%)两种并发症发生情况方面,较对照组相比,优势显著(P<0.05)。结论应将枸橼酸咖啡因联合NCPAP用于早产儿频繁呼吸暂停的临床治疗,提高治疗有效率,降低心动过速与血糖异常发生几率,使患儿能够尽快康复。
Objective To investigate the efficacy of citrate caffeine combined with NCPAP in the treatment of frequent apnea in preterm infants. Methods Totally 62 infants with frequent apnea who were admitted to our hospital were selected as the samples and randomly divided into experimental group and control group. Control children with conventional NCPAP treatment, the experimental group of children with citrate caffeine combined with NCPAP treatment. During the treatment, complications of the two groups were observed. After treatment for 24 hours, the number of apnea episodes in both groups was observed to determine the therapeutic effect. Results The effective rate of treatment in children in control group was 77.42%, and that in experimental group was 96.77%. The advantage of the latter was significant (P <0.05). Compared with the control group, the children in the experimental group had significant advantages (P <0.05) in the complication of tachycardia (3.22%) and abnormal blood glucose (6.45%). Conclusions Citrate caffeine combined with NCPAP should be used in the clinical treatment of frequent apnea in premature infants, to improve the treatment efficiency and reduce the incidence of tachycardia and abnormal blood glucose, so that children can recover quickly.