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喉癌是呼吸道常见的恶性肿瘤，术后失声和永久性气管病口是喉癌患者两大痛苦。喉癌疗效有赖于对其生物学行为及预后影响因素的深刻认识。初次治疗后复发的患者若能在复发的早期发现，仍可通过适当的治疗（手术或放疗）治愈。因此，有必要寻求一种能提示肿瘤残留或复发的肿瘤标
Laryngeal cancer is a common malignant tumor of the respiratory tract, postoperative loss of sound and permanent tracheal disease is two major pain in patients with laryngeal cancer. The efficacy of laryngeal cancer depends on its biological behavior and prognostic factors. Patients who have relapsed after initial treatment may still be cured by appropriate treatment (surgery or radiotherapy) if they are found early in the relapse. Therefore, it is necessary to seek a kind of tumor markers that can prompt the residual or recurrence of tumor