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[目的]了解四川省干部人群糖代谢异常的患病情况并分析其危险因素,为制定适宜的干预措施提供依据。[方法]选用2009年在某院健康体检的干部人群,分别进行身高体重血压测定、糖耐量试验(OGTT)及生化指标检查等。糖代谢异常的诊断依据WHO1999年糖尿病的诊断标准。运用多因素非条件Logistic回归分析,探讨影响糖代谢异常发生的危险因素。[结果](1)糖代谢异常总检出率为33.2%,其中DM的检出率7.3%,糖调节受损(IGR,糖尿病前期)总的检出率为25.8%,IGR各亚组的检出率分别为:I-IFG1.9%、I-IGT20.3%及IFG/IGT3.6%。(2)糖代谢异常组的体重指数(BMI)、腰臀比(WHR)、甘油三醋(TG)、收缩压(SBP)、血肌酐(Cr)测值均较NGT组高,且差异有统计学意义(P﹤0.01或P﹤0.05),而HDL-C较NGT组低,差异有统计学意义(P﹤0.05)。(3)年龄、BMI、WHR、TG是糖代谢异常的危险因素(P﹤0.05或P﹤0.01)。[结论]四川省干部人群糖代谢异常率高。年龄、BMI、WHR、TG为糖代谢异常的主要危险因素。
[Objective] To understand the prevalence of glycometabolism abnormalities among cadres in Sichuan province and to analyze the risk factors for them, and to provide basis for making appropriate interventions. [Methods] The cadres who took physical examination in a hospital in 2009 were tested for height-weight and blood pressure, glucose tolerance test (OGTT) and biochemical indexes. The diagnosis of abnormal glucose metabolism is based on the WHO diagnostic criteria for childhood diabetes in 1999. Multivariate non-conditional logistic regression analysis was used to explore the risk factors influencing the occurrence of abnormal glucose metabolism. [Results] (1) The total detection rate of abnormal glucose metabolism was 33.2%, of which the detection rate of DM was 7.3%, the total detection rate of impaired glucose regulation (IGR, pre-diabetes) was 25.8% The detection rates were: I-IFG 1.9%, I-IGT 20.3% and IFG / IGT 3.6%. (2) Body mass index (BMI), WHR, triglyceride (TG), systolic blood pressure (SBP) and serum creatinine (Cr) in abnormal glucose metabolism group were higher than those in NGT group Statistical significance (P <0.01 or P <0.05), while HDL-C was lower than that of NGT group (P <0.05). (3) Age, BMI, WHR, TG were the risk factors of abnormal glucose metabolism (P <0.05 or P <0.01). [Conclusion] The rate of abnormal glucose metabolism in Sichuan cadres is high. Age, BMI, WHR, TG are the main risk factors of abnormal glucose metabolism.