Rotavirus is the most common etiologic agent of severe diarrhea in infants and young children and causes more than 200,000 deaths annually worldwide [1,2].Licensed rotavirus vaccines can provide more than 50％ protection against rotavirus infection, and currently available etiological treatments for rotavirus gastroenteritis mainly involve the use of oral rehydration solution and zinc supplementation [3].However, targeted interventions are in great need for rotavirus-induced gastroenteritis control.