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本文对本院1985.1～1986.3入院的各型流行性脑脊髓膜炎(简称流脑)患儿63例,于入院时(治疗前)、好转期及恢复期,用同位素放射免疫法测其血中皮质醇含量,以观察其肾上腺皮质功能,说明各型流脑患儿(轻型、普通型、重型)于入院时治疗前其血中皮质醇含量均升高,好转期下降,至恢复期趋于正常。另可见到入院时治疗前其血中皮质醇浓度高低与流脑的临床类型有关。并提出在临床上并非所有流脑患儿在感染早期即应用皮质激素治疗,在严重暴发型死亡病例血中皮质醇浓度并不很高,故应早用大剂量皮质激素治疗。
In our hospital from 1985.1 to 1986.3 admission of all types of epidemic meningitis (referred to as meningitis) 63 cases of children admitted to hospital (before treatment), during the transition and recovery, using radioimmunoassay to measure the blood Cortisol content in order to observe the function of adrenocortical, indicating that children with all kinds of meningitis (light, common, heavy) in the hospital before treatment, the blood cortisol levels were elevated, decreased during the transition to the recovery period tends to normal. The other can be seen when admission to the hospital before treatment, the level of cortisol in the blood and the clinical type of meningitis. And proposed that clinically not all patients with meningitis in early infection that corticosteroid treatment in the case of severe deaths of blood cortisol concentrations are not high, it should be early with high-dose corticosteroids.