感染是白血病患者病势恶化及致死的主要原因。急性淋巴细胞白血病(简称ALL)的缓解率在小儿已达90％以上,有效的维持疗法也使ALL中数生存期超过5年。然而,尽管癌肿病人的抗菌素治疗取得了进展,但是败血症仍是可怕的诊断和治疗的难题。作者研究儿童ALL中50例次败血症,为了阐明何种细菌是病原以及中性白细胞水平和发生败血症之间比较密切的相互关系。材料和方法 75例儿童ALL发生50例次败血症,其中没有一例进行脾切除或接受过预防性抗菌素。第一次诱导缓解是用长春新碱、强的松、门冬酰胺酶,接着进行中枢神经系统的预防(鞘内注 Infection is the main reason for the worsening and lethality of leukemia patients. Acute lymphoblastic leukemia (ALL) response rate has reached more than 90% in children, effective maintenance therapy also ALL median survival of more than 5 years. However, despite advances in antibiotic treatment of cancer patients, sepsis remains a daunting diagnosis and treatment challenge. The authors studied 50 sepsis sepsis in children with ALL, in order to elucidate which bacteria are pathogenic as well as neutrophil levels and the occurrence of sepsis between the more closely related. MATERIALS AND METHODS Fifty septicemic seizures were reported in 75 children with ALL, none of whom underwent splenectomy or received prophylactic antibiotics. The first induction of remission is with vincristine, prednisone, asparaginase, followed by the prevention of the central nervous system (intrathecal injection