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头孢菌素类抗生素是一类疗效和安全性好、临床应用广泛的抗菌药物,但由于可能引发过敏反应,故有学者认为须在注射给药前进行皮肤敏感试验(以下简称为“皮试”)。但对头孢菌素类抗生素是否必须进行皮试、如何进行皮试和皮试的临床意义等问题,目前国内、外均还无定论。本文介绍头孢菌素类抗生素导致过敏反应发生的机制,归纳国外对临床使用头孢菌素类抗生素前进行皮试的必要性的研究结果,发现虽观点不一,但认为进行头孢菌素类抗生素皮试意义不大的依据较强。
Cephalosporins antibiotics are a class of anti-bacterial drugs with good curative effect and safety and wide range of clinical application. However, some scholars think that sensitive skin test should be performed before injection (hereinafter referred to as “skin test” "). However, cephalosporins antibiotics must be skin test, how the skin test and skin test clinical significance and other issues, at home and abroad are still inconclusive. This article describes the mechanism of cephalosporin antibiotics lead to allergic reactions, induction of foreign clinical trials of cephalosporin antibiotics before the need for skin test results and found that although the different opinions, but that the cephalosporin antibiotics skin Less significant on the basis of a strong test.