To reduce the discrepancy between the source and target domains,a new multi-label adaptation network(ML-ANet)based on multiple kernel variants with maximum mean discrepancies is proposed in this paper.The hidden represen-tations of the task-specific layers in ML-ANet are embedded in the reproducing kernel Hilbert space(RKHS)so that the mean-embeddings of specific features in different domains could be precisely matched.Multiple kernel functions are used to improve feature distribution efficiency for explicit mean embedding matching,which can further reduce domain discrepancy.Adverse weather and cross-camera adaptation examinations are conducted to verify the effec-tiveness of our proposed ML-ANet.The results show that our proposed ML-ANet achieves higher accuracies than the compared state-of-the-art methods for multi-label image classification in both the adverse weather adaptation and cross-camera adaptation experiments.These results indicate that ML-ANet can alleviate the reliance on fully labeled training data and improve the accuracy of multi-label image classification in various domain shift scenarios.